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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX3X All Species: 17.58
Human Site: S28 Identified Species: 27.62
UniProt: O00571 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00571 NP_001347.3 662 73243 S28 L N S S D N Q S G G S T A S K
Chimpanzee Pan troglodytes Q6GVM6 660 73172 Q26 L D L N S E K Q S G G A S R A
Rhesus Macaque Macaca mulatta XP_001095294 910 100218 S278 L N S S D N Q S G G S T A S K
Dog Lupus familis XP_861268 662 73195 S28 L N S S D N Q S G G S T A S K
Cat Felis silvestris
Mouse Mus musculus Q62167 662 73083 S28 L N S S D N Q S G G S T A S K
Rat Rattus norvegicus NP_001102328 659 72976 S26 L D L T S P D S Q S G A S T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512924 651 71975 K22 S G G S T A S K G R Y I P P H
Chicken Gallus gallus NP_001025971 651 72031 S26 L D L N S S D S Q S E G S A T
Frog Xenopus laevis P24346 697 77284 D69 G Y I N G M Q D D R D G R M N
Zebra Danio Brachydanio rerio NP_571016 688 75828 G56 A P G G W D N G R S N G F V N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHP0 798 85063 F143 D N Y N G G E F D S R R G G D
Honey Bee Apis mellifera XP_391829 701 78642 R71 D R G R D R D R E R E R E R D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M2F9 646 69224 G22 A P S G G G W G Y S R P S R T
Baker's Yeast Sacchar. cerevisiae P24784 617 67899 E17 N L S I N N K E N G G G G G K
Red Bread Mold Neurospora crassa Q9P6U9 688 72037 K42 I P P H L R G K M G D A A P P
Conservation
Percent
Protein Identity: 100 91.3 70.1 99.8 N.A. 98.6 95.3 N.A. 95.9 91.2 82.2 76.3 N.A. 51.7 58 N.A. N.A.
Protein Similarity: 100 95.3 70.3 99.8 N.A. 99 97.1 N.A. 97.2 94.7 88 83.8 N.A. 63.4 70 N.A. N.A.
P-Site Identity: 100 13.3 100 100 N.A. 100 13.3 N.A. 13.3 13.3 6.6 0 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 40 100 100 N.A. 100 40 N.A. 13.3 46.6 13.3 13.3 N.A. 20 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.5 49.4 52
Protein Similarity: N.A. N.A. N.A. 64.6 65.2 64.8
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 13.3
P-Site Similarity: N.A. N.A. N.A. 13.3 40 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 0 0 7 0 0 0 0 0 20 34 7 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 20 0 0 34 7 20 7 14 0 14 0 0 0 14 % D
% Glu: 0 0 0 0 0 7 7 7 7 0 14 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 7 0 0 % F
% Gly: 7 7 20 14 20 14 7 14 34 47 20 27 14 14 0 % G
% His: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 7 0 7 7 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 0 0 0 0 14 14 0 0 0 0 0 0 34 % K
% Leu: 47 7 20 0 7 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 7 0 0 7 0 0 0 0 7 0 % M
% Asn: 7 34 0 27 7 34 7 0 7 0 7 0 0 0 14 % N
% Pro: 0 20 7 0 0 7 0 0 0 0 0 7 7 14 7 % P
% Gln: 0 0 0 0 0 0 34 7 14 0 0 0 0 0 0 % Q
% Arg: 0 7 0 7 0 14 0 7 7 20 14 14 7 20 0 % R
% Ser: 7 0 40 34 20 7 7 40 7 34 27 0 27 27 0 % S
% Thr: 0 0 0 7 7 0 0 0 0 0 0 27 0 7 14 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 7 0 0 0 0 0 7 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _